Azide-PEG1-Val-Cit-PABC-OH, CAS 2055041-40-0

Product Description: Azide-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C23H36N8O6

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 2055041-40-0

Molecular Weight: 520.58

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• Artikelnummer: MEXHY-136137-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-136137-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK