Azido-PEG4-C2-acid, CAS 1257063-35-6

Product Description: Azido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: COVID-19-immunoregulation

Formula: C11H21N3O6

References: [1]Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231.

CAS Number: 1257063-35-6

Molecular Weight: 291.30

Compound Purity: 98.0

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• Artikelnummer: MEXHY-130653-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-130653-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK