Azido-PEG5-alcohol, CAS 86770-68-5

Product Description: Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C10H21N3O5

References: [1]Zhang FL, et al. Molecular-target-based anticancer photosensitizer: synthesis and in vitro photodynamic activity of erlotinib-zinc(II) phthalocyanine conjugates. ChemMedChem. 2015 Feb;10(2):312-20./[2] Nan JI, et al. Mertk degraders and uses thereof. WO2020010210A1.

CAS Number: 86770-68-5

Molecular Weight: 263.29

Compound Purity: 97.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• Artikelnummer: MEXHY-130211-5G
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-130211-5G
• Green Labware: Nein
• Verpackungseinheit: 5 g
• Mengeneinheit: STK