Azido-PEG8-NHS ester, CAS 1204834-00-3

Product Description: Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C23H40N4O12

References: [1]Mahendra Persaud Deonarain, et al. Biological materials and uses thereof. WO2016046574A1./[2]Rong Yuan, et al. Viruslike Element-Tagged Nanoparticle Inductively Coupled Plasma Mass Spectrometry Signal Multiplier: Membrane Biomarker Mediated Cell Counting. Analytical Chemistry (Washington, DC, United States) (2019), 91(8), 4948-4952.

CAS Number: 1204834-00-3

Molecular Weight: 564.58

Compound Purity: 97.0

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• Artikelnummer: MEXHY-130184-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-130184-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK