Azidoethyl-SS-propionic NHS ester, CAS 2243566-44-9

Product Description: Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C9H12N4O4S2

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 2243566-44-9

Molecular Weight: 304.35

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• Artikelnummer: MEXHY-140102-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-140102-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK