Product Description: Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-C16-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs Applications: Cancer-programmed cell death
Formula: C22H42O4
References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337./[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
CAS Number: 843666-40-0
Molecular Weight: 370.57
Compound Purity: 99.98
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)