Brigimadlin intermediate-1, CAS 1149388-04-4

Brigimadlin intermediate-1, CAS 1149388-04-4
Artikelnummer
MEXHY-W598456-0
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MedChemExpress

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Product Description: Brigimadlin intermediate-1 is an intermediate of the E3 ubiquitin protein ligase MDM-2 inhibitor Brigimadlin (HY-152859) and can be used to synthesize Antibody-Drug Conjugates (ADCs) .

Formula: C9H10N2O4

References: [1]Gollner Andreas, et al. Preparation of spiroindolepyrrolidinone derivatives for use as MDM2-p53 inhibitors: World Intellectual Property Organization, WO2017060431. 2017-04-13./[2]WHO Drug Information-World Health Organization (WHO)./[3]Hao X, et al. BI-907828, a novel potent MDM2 inhibitor, inhibits glioblastoma brain tumor stem cells in vitro and prolongs survival in orthotopic xenograft mouse models. Neuro Oncol. 2023 May 4;25(5):913-926.

CAS Number: 1149388-04-4

Molecular Weight: 210.19

Research Area: cancer

Solubility: 10 mM in DMSO

Target: Others
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Artikelnummer MEXHY-W598456-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-W598456-0
Green Labware Nein
Verpackungseinheit Get quote
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