Bromo-PEG2-C2-azide, CAS 530151-56-5

Product Description: Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bromo-PEG2-C2-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG2-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C6H12BrN3O2

References: [1]Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.

CAS Number: 530151-56-5

Molecular Weight: 238.08

Compound Purity: 98.10

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• Artikelnummer: MEXHY-130485-250
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-130485-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK