Product Description: CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor[1].
Applications: Cancer-programmed cell death
Formula: C87H116N14O24
References: [1]Lianqi Liu, et al. Synthesis and evaluation of highly releasable and structurally stable antibody-SN-38-conjugates. Drug Deliv. 2021 Dec;28(1):2603-2617.
CAS Number: 1639139-65-3
Molecular Weight: 1741.93
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Drug-Linker Conjugates for ADC