Cyclooctyne-O-NHS ester, CAS 1425803-45-7

Product Description: Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C14H17NO5

References: [1]Tao Wang, et al. Design and synthesis of tumor-targeting theranostic drug conjugates for SPECT and PET imaging studies. Bioorg Chem. 2018 Feb;76:458-467.

CAS Number: 1425803-45-7

Molecular Weight: 279.29

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker

• Artikelnummer: MEXHY-126517-500
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-126517-500
• Green Labware: Nein
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK