DBCO-NHCO-PEG4-NHS ester, CAS 2100306-58-7

Product Description: DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C34H39N3O10

References: [1]Thornlow DN, et al. Dual Site-Specific Antibody Conjugates for Sequential and Orthogonal Cargo Release. Bioconjug Chem. 2019 Jun 19;30(6):1702-1710.

CAS Number: 2100306-58-7

Molecular Weight: 649.69

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• Artikelnummer: MEXHY-111456-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-111456-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK