DC4SMe, CAS 615538-47-1

Product Description: DC4SMe, a phosphate proagent of cytotoxic DNA alkylator DC4, can be used in the synthesis of antibody-drug conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer[1].

Applications: Cancer-programmed cell death

Formula: C35H31ClN5O7PS2

References: [1]Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.

CAS Number: 615538-47-1

Molecular Weight: 764.21

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin

• Artikelnummer: MEXHY-135123-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-135123-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK