DGN549-C, CAS 2058075-34-4

Product Description: DGN549-C consists a cleavable ADC linker valine-alanine (va) and PBD dimer. DGN549 is a novel DNA-alkylating cytotoxic payload and can be used in the synthesis of antibody-agent conjugates (ADCs)[1].

Applications: Cancer-programmed cell death

Formula: C60H61N9O12

References: [1]Chen Bai, et al. Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody-Drug Conjugates With an Improved Therapeutic Index as Compared With Lysine Conjugation. Bioconjug Chem

CAS Number: 2058075-34-4

Molecular Weight: 1100.18

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• Artikelnummer: MEXHY-136297-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-136297-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK