Dideoxy-amanitin, CAS 58255-46-2

Product Description: Dideoxy-amanitin (compound 2), an α-Amanitin (HY-19610) derivative, is a potent and selective RNA polymerase II allosteric inhibitor with an IC50 value of 74.2 nM[1].

Applications: Cancer-programmed cell death

Formula: C39H54N10O12S

References: [1]Matinkhoo K, et, al. Design, Synthesis, and Biochemical Evaluation of Alpha-Amanitin Derivatives Containing Analogs of the trans-Hydroxyproline Residue for Potential Use in Antibody-Drug Conjugates. Chemistry. 2021 Jul 16;27(40):10282-10292.

CAS Number: 58255-46-2

Molecular Weight: 886.97

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin;DNA/RNA Synthesis

• Artikelnummer: MEXHY-148231-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-148231-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK