Mal-PEG4-bis-PEG3-methyltetrazine

Mal-PEG4-bis-PEG3-methyltetrazine
Artikelnummer
MEXHY-130953-0
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MedChemExpress

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Product Description: Mal-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Mal-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

Applications: Cancer-programmed cell death

Formula: C65H95N15O20

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Weight: 1406.54

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker
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Artikelnummer MEXHY-130953-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-130953-0
Green Labware Nein
Verpackungseinheit Get quote
Mengeneinheit STK
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