Maytansinoid B, CAS 1628543-40-7

Product Description: Maytansinoid B is a kind of ADC Cytotoxin. Maytansinoid B can be used to conjugates with antibodies to form antibody-drug conjugates (ADCs). Maytansinoids are known as antimitotic agents, binding to tubulin and inhibiting microtubule assembly. Maytansinoids induces G2/M arrest in the cell cycle to induce apoptosis[1][2].

Applications: Cancer-programmed cell death

Formula: C36H51ClN4O10

References: [1]Blanc V, et al. SAR3419: an anti-CD19-Maytansinoid Immunoconjugate for the treatment of B-cell malignancies. Clin Cancer Res. 2011 Oct 15;17(20):6448-58. /[2]Andreev Julian, et al. Bispecific antigen binding molecules that bind HER2, and methods of use thereof: World Intellectual Property Organization, WO2021174113. 2021-09-02.

CAS Number: 1628543-40-7

Molecular Weight: 735.26

Compound Purity: 99.06

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Cytotoxin

• Artikelnummer: MEXHY-148870-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-148870-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK