MC-GGFG-Exatecan, CAS 1600418-29-8

Product Description: MC-GGFG-Exatecan (MC-GGFG-DX8951) is a agent-linker conjugate for ADC. MC-GGFG-Exatecan is a DX8951 (a DNA topoisomerase I inhibitor) derivative with protease cleavable MC-GGFG linker. MC-GGFG-Exatecan shows antitumor activity and can be used to prepare DX8951 antibody conjugate (ADC)[1].

Applications: Cancer-programmed cell death

Formula: C49H51FN8O11

References: [1]Nakada T, et al. Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1542-1545.

CAS Number: 1600418-29-8

Molecular Weight: 946.97

Compound Purity: 99.71

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC;Topoisomerase

• Artikelnummer: MEXHY-114233-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-114233-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK