MC-Sq-Cit-PAB-Gefitinib, CAS 1941168-63-3

Product Description: MC-Sq-Cit-PAB-Gefitinib is a agent-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.

Applications: Cancer-Kinase/protease

Formula: C50H61ClFN10O9

References: [1]FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1./[2]Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

CAS Number: 1941168-63-3

Molecular Weight: 1000.53

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• Artikelnummer: MEXHY-128893-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-128893-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK