Product Description: N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) )[1].
Applications: Cancer-programmed cell death
Formula: C9H13NO3
References: [1] Finniss, M. C., et al. A versatile acid-labile linker for antibody–drug conjugates. Med. Chem. Commun., 2014, 5(9), 1355-1358.
CAS Number: 180608-78-0
Molecular Weight: 183.20
Compound Purity: 99.89
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: ADC Linker