N3-PEG5-aldehyde, CAS 2566404-73-5

Product Description: N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C20H30N4O7

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 2566404-73-5

Molecular Weight: 438.47

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• Artikelnummer: MEXHY-136054-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-136054-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK