NH2-PEG4-hydrazone-DBCO

NH2-PEG4-hydrazone-DBCO
Artikelnummer
MEXHY-136131-25
Verpackungseinheit
25mg
Hersteller
MedChemExpress

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Product Description: NH2-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. NH2-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C37H43N5O7

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Weight: 669.77

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker
Mehr Informationen
Artikelnummer MEXHY-136131-25
Hersteller MedChemExpress
Hersteller Artikelnummer HY-136131-25
Green Labware Nein
Verpackungseinheit 25mg
Mengeneinheit STK
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