SGD-1910, CAS 1342820-51-2

Product Description: SGD-1910 is a agent-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala[1].

Applications: Cancer-programmed cell death

Formula: C60H64N8O12

References: [1]John A Hartley. Antibody-drug conjugates (ADCs) delivering pyrrolobenzodiazepine (PBD) dimers for cancer therapy. Expert Opin Biol Ther. 2020 Jun 16;1-13./[2]Jeffrey SC, et al. A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology. Bioconjug Chem. 2013 Jul 17;24(7):1256-63.

CAS Number: 1342820-51-2

Molecular Weight: 1089.20

Compound Purity: 95.95

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC

• Artikelnummer: MEXHY-101162-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-101162-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK