SN38-COOH, CAS 2170118-23-5

Product Description: SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis[1][2].

Applications: Cancer-programmed cell death

Formula: C26H24N2O8

References: [1]Wilson Lim, et al. Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma. PLoS Negl Trop Dis. 2018 Apr 26;12(4):e0006437./[2]Wallin A, et al. Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. Oncol Rep. 2008 Jun;19(6):1493-8.

CAS Number: 2170118-23-5

Molecular Weight: 492.48

Compound Purity: 98.85

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Drug-Linker Conjugates for ADC

• Artikelnummer: MEXHY-153013-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-153013-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK