sulfo-DGN462 (sodium), CAS 1401203-09-5

Product Description: sulfo-DGN462 sodium is degraded to DGN462 in culture medium and plasma. DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML)[1].

Applications: Cancer-programmed cell death

Formula: C53H60N5NaO12S2

References: [1]Hicks SW, et al. The novel CD19-targeting antibody-drug conjugate huB4-DGN462 shows improved anti-tumor activity compared to SAR3419 in CD19-positive lymphoma and leukemia models. Haematologica. 2019 Aug;104(8):1633-1639.

CAS Number: 1401203-09-5

Molecular Weight: 1046.19

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin;DNA Alkylator/Crosslinker

• Artikelnummer: MEXHY-101150A-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-101150A-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK