Taltobulin, CAS 228266-40-8

Product Description: Taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis[1].

Applications: Cancer-programmed cell death

Formula: C27H43N3O4

References: [1]Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45.

CAS Number: 228266-40-8

Molecular Weight: 473.65

Compound Purity: 99.90

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: ADC Cytotoxin;Apoptosis;Microtubule/Tubulin

• Artikelnummer: MEXHY-15584-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15584-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK