Taltobulin (trifluoroacetate), CAS 228266-41-9

Product Description: Taltobulin trifluoroacetate (HTI-286 trifluoroacetate), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis[1].

Applications: Cancer-programmed cell death

Formula: C29H44F3N3O6

References: [1]Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45.

CAS Number: 228266-41-9

Molecular Weight: 587.67

Compound Purity: 99.08

Research Area: Cancer

Solubility: DMSO : ≥ 39 mg/mL

Target: ADC Cytotoxin;Apoptosis;Microtubule/Tubulin

• Artikelnummer: MEXHY-15584A-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15584A-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK