Trastuzumab emtansine, CAS 1018448-65-1

Product Description: Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine). Trastuzumab emtansine can be used for the research of advanced breast cancer[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Verma S, et, al. Trastuzumab emtansine for HER2-positive advanced breast cancer. N Engl J Med. 2012 Nov 8;367(19):1783-91./[2]Menderes G, et, al. Superior in vitro and in vivo activity of trastuzumab-emtansine (T-DM1) in comparison to trastuzumab, pertuzumab and their combination in epithelial ovarian carcinoma with high HER2/neu expression. Gynecol Oncol. 2017 Oct;147(1):145-152.

CAS Number: 1018448-65-1

Molecular Weight: 148000 (average)

Compound Purity: 99.74

Research Area: Cancer

Solubility: H2O

Target: Antibody-Drug Conjugates (ADCs);EGFR

• Artikelnummer: MEXHY-P9921-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P9921-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK