Abelacimab, CAS 2098724-83-3

Abelacimab, CAS 2098724-83-3
Artikelnummer
MEXHY-P99415-5
Verpackungseinheit
5 mg
Hersteller
MedChemExpress

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Product Description: Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies[1][2].

Applications: Neuroscience-Neuromodulation

Formula: N/A

References: [1]Alexander W Koch, et al. MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans. Blood. 2019 Mar 28;133(13):1507-1516./[2]Elena Campello, et al. Clinical Pharmacology of Factor XI Inhibitors: New Therapeutic Approaches for Prevention of Venous and Arterial Thrombotic Disorders. J Clin Med. 2022 Oct 26;11(21):6314.

CAS Number: 2098724-83-3

Molecular Weight: N/A

Compound Purity: 98.63

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Factor Xa
Mehr Informationen
Artikelnummer MEXHY-P99415-5
Hersteller MedChemExpress
Hersteller Artikelnummer HY-P99415-5
Green Labware Nein
Verpackungseinheit 5 mg
Mengeneinheit STK
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