Acasunlimab, CAS 2253937-12-9

Product Description: Acasunlimab (GEN1046) is a bispecific antibody (bsAb) targeting PD-L1 and 4-1BB. Acasunlimab enhances T-cell and NK-cell function through conditional 4-1BB stimulation while constitutively blocking the PD-1/PD-L1 inhibitory axis. Acasunlimab can be used in research of cancer[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Muik A, et, al. Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors. Cancer Discov. 2022 May 2;12(5):1248-1265./[2]Gao Y, et, al. Development and characterization of a novel human CD137 agonistic antibody with anti-tumor activity and a good safety profile in non-human primates. FEBS Open Bio. 2022 Dec;12(12):2166-2178.

CAS Number: 2253937-12-9

Molecular Weight: N/A

Compound Purity: 99.90

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PD-1/PD-L1

• Artikelnummer: MEXHY-P99419-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99419-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK