Adecatumumab, CAS 503605-66-1

Product Description: Adecatumumab (Anti-Human EPCAM Recombinant Antibody; MT201) is a full human monoclonal antibody of the IgG1 isotype, targeting human EpCAM. Adecatumumab is expressed in almost all adenocarcinomas, and its activity is not dependent of K-Ras status[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Kurtz JE, et al. Adecatumumab: an anti-EpCAM monoclonal antibody, from the bench to the bedside. Expert Opin Biol Ther. 2010 Jun;10(6):951-8. /[2]Lutterbuese P, et al. Exchanging human Fcgamma1 with murine Fcgamma2a highly potentiates anti-tumor activity of anti-EpCAM antibody adecatumumab in a syngeneic mouse lung metastasis model. Cancer Immunol Immunother. 2007 Apr;56(4):459-68.

CAS Number: 503605-66-1

Molecular Weight: N/A

Compound Purity: 99.54

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• Artikelnummer: MEXHY-P99278-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99278-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK