Bentracimab, CAS 2260568-31-6

Product Description: Bentracimab (PB 2452) is a neutralizing monoclonal antibody that binds Ticagrelor (HY-1006) and its major active circulating metabolite with high affinity. Bentracimab can rapidly reverse the antiplatelet effect of Ticagrelor[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: N/A

References: [1]Kathman SJ, et, al. Population pharmacokinetic-pharmacodynamic modeling of PB2452, a monoclonal antibody fragment being developed as a ticagrelor reversal agent, in healthy volunteers. CPT Pharmacometrics Syst Pharmacol. 2022 Jan;11(1):68-81./[2]Almquist J, et, al. Unraveling the pharmacokinetic interaction of ticagrelor and MEDI2452 (Ticagrelor antidote) by mathematical modeling. CPT Pharmacometrics Syst Pharmacol. 2016 Jun;5(6):313-23.

CAS Number: 2260568-31-6

Molecular Weight: N/A

Research Area: Metabolic Disease

Solubility: H2O

Target: Others

• Artikelnummer: MEXHY-P99469-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99469-1
• Verpackungseinheit: 1mg
• Mengeneinheit: STK
• Konjugat: Unconjugated