Clervonafusp alfa, CAS 2145123-44-8

Product Description: Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha glucosidase (rhGAA), the former utilizing the nucleoside transporter ENT-2 to gain access to the cytosol, and the latter enters lysosomes via mannose-6-phosphate receptors (M6PRs). Clervonafusp alfa can be used for late-onset Pompe disease research[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: N/A

References: [1]Kishnani P, et al. Safety and efficacy of VAL-1221, a novel fusion protein targeting cytoplasmic glycogen, in patients with late-onset Pompe disease. Molecular Genetics & Metabolism, 2019, 126(2):S85-S86.

CAS Number: 2145123-44-8

Molecular Weight: N/A

Research Area: Others

Solubility: H2O

Target: Glucosidase

• Artikelnummer: MEXHY-P99803-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99803-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK
• Konjugat: Unconjugated