Daratumumab (PBS), CAS 945721-28-8

Product Description: Daratumumab (PBS) (Anti-Human CD38) is the first-in-class human-specific anti-CD38 monoclonal antibody (IgG1). Daratumumab (PBS) has anti-multiple myeloma (MM) effect. Daratumumab (PBS) impairs MM cell adhesion, which results in an increased sensitivity of MM to proteasome inhibition[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Ghose J, Viola D, et al. Daratumumab induces CD38 internalization and impairs myeloma cell adhesion. Oncoimmunology. 2018;7(10):e1486948. Published 2018 Jul 23./[2]de Weers M, et al. Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors. J Immunol. 2011;186(3):1840-1848.

CAS Number: 945721-28-8

Molecular Weight: N/A

Compound Purity: 95.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Antibody;CD38

• Artikelnummer: MEXHY-P9915A-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P9915A-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK