Product Description: Domagrozumab is an anti-myostatin humanized monoclonal antibody with a KD value of 2.6 pM for human myostatin. Domagrozumab induces muscle anabolic activity. Domagrozumab can be used in research of duchenne muscular dystrophy (DMD)[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: N/A
References: [1]St Andre M, et, al. A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys. Skelet Muscle. 2017 Nov 9;7(1):25.
CAS Number: 1629605-31-7
Molecular Weight: N/A
Compound Purity: 96.34
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Others