Product Description: Durvalumab (anti-PD-L1)(MEDI 4736) is a human anti-PD-L1 protein monoclonal antibody[1]. Durvalumab (anti-PD-L1) completely blocks PD-L1 binding to PD-1 and CD80, IC 50 are 0.1 and 0.04 nM[1] respectively[1][2].
Formula: N/A
References: [1]Faiena I, et al. Durvalumab: an investigational anti-PD-L1 monoclonal antibody for the treatment of urothelial carcinoma. Drug Des Devel Ther. 2018 Jan 23;12:209-215./[2]Stewart R, et al. Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody. Cancer Immunol Res. 2015 Sep;3(9):1052-62.
CAS Number: 1428935-60-7
Molecular Weight: N/A
Compound Purity: 99.90
Research Area: Others
Solubility: 10 mM in DMSO
Target: PD-1/PD-L1