Durvalumab, CAS 1428935-60-7

Product Description: Durvalumab (MEDI 4736) is an human anti-PD-L1 monoclonal antibody[1]. Durvalumab (MEDI4736) completely blocks the binding of PD-L1 to both PD-1 and CD80, with IC50s of 0.1 and 0.04 nM, respectively[2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Stewart R, et al. Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody. Cancer Immunol Res. 2015 Sep;3(9):1052-62./[2]Faiena I, et al. Durvalumab: an investigational anti-PD-L1 monoclonal antibody for the treatment of urothelial carcinoma. Drug Des Devel Ther. 2018 Jan 23;12:209-215.

CAS Number: 1428935-60-7

Molecular Weight: N/A

Compound Purity: 99.60

Research Area: Cancer

Solubility: H2O

Target: PD-1/PD-L1

• Artikelnummer: MEXHY-P9919-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P9919-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK