Eftozanermin alfa, CAS 1820660-69-2

Product Description: Eftozanermin alfa (ABBV-621) is a second-generation tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors 4/5. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Tahir SK, et al. Activity of eftozanermin alfa plus venetoclax in preclinical models and patients with acute myeloid leukemia. Blood. 2023 Jan 30:blood.2022017333./[2]Silva A S, et al. Ex Vivo Drug Sensitivity and Functional Genomics Platform Identifies Novel Combinations Targeting Intrinsic and Extrinsic Apoptotic Signaling Pathways in Multiple Myeloma. Blood, 2020, 136(Supplement 1):49-50.

CAS Number: 1820660-69-2

Molecular Weight: N/A

Compound Purity: 95.40

Research Area: Cancer

Solubility: H2O

Target: Apoptosis

• Artikelnummer: MEXHY-P99934-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99934-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Konjugat: Unconjugated