Emactuzumab, CAS 1448221-67-7

Product Description: Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor (CSF1R) activation. Emactuzumab has high affinity for CSF-1R with Ki value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) [1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Philippe A Cassier, et al. CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study. Lancet Oncol. 2015 Aug;16(8):949-56./[2]Carola H Ries, et al. Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy. Cancer Cell. 2014 Jun 16;25(6):846-59.

CAS Number: 1448221-67-7

Molecular Weight: N/A

Compound Purity: 97.60

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: c-Fms

• Artikelnummer: MEXHY-P99245-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99245-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK