Emapalumab, CAS 1709815-23-5

Product Description: Emapalumab (NI-0501) is a human monoclonal IgG1 antibody that noncompetitively inhibits IFN-γ. Emapalumab binds with high affinity (Kd= 1.4 pM) to both free IFN-γ as well as IFN-γ bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH)[1].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Vallurupalli M, et, al. Emapalumab for the treatment of relapsed/refractory hemophagocytic lymphohistiocytosis. Blood. 2019 Nov 21;134(21):1783-1786.

CAS Number: 1709815-23-5

Molecular Weight: N/A

Compound Purity: 98.86

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: IFNAR

• Artikelnummer: MEXHY-P99191-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99191-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK