Epcoritamab, CAS 2134641-34-0

Product Description: Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]van der Horst HJ, et al. Epcoritamab induces potent anti-tumor activity against malignant B-cells from patients with DLBCL, FL and MCL, irrespective of prior CD20 monoclonal antibody treatment. Blood Cancer J. 2021 Feb 18;11(2):38. /[2]Thieblemont C, et al. Epcoritamab, a Novel, Subcutaneous CD3xCD20 Bispecific T-Cell-Engaging Antibody, in Relapsed or Refractory Large B-Cell Lymphoma: Dose Expansion in a Phase I/II Trial. J Clin Oncol. 2023 Apr 20;41(12):2238-2247.

CAS Number: 2134641-34-0

Molecular Weight: N/A

Compound Purity: 99.84

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: CD20;CD3

• Artikelnummer: MEXHY-P99931-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99931-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK