Ezabenlimab, CAS 2249882-54-8

Product Description: Ezabenlimab (BI-754091) is an anti-PD-1 mAb with binding constant Kd value of 6 nM (CHO cells). Ezabenlimab blocks the interaction of PD-1 with PD-L1 and PD-L2. Ezabenlimab increases interferon-γ secretion in T cells, and inhibits tumor growth in vivo[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Zettl M, et al. Combination of two novel blocking antibodies, anti-PD-1 antibody ezabenlimab (BI 754091) and anti-LAG-3 antibody BI 754111, leads to increased immune cell responses. Oncoimmunology. 2022 Jun 16;11(1):2080328.

CAS Number: 2249882-54-8

Molecular Weight: N/A

Compound Purity: 99.82

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PD-1/PD-L1

• Artikelnummer: MEXHY-P99610-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99610-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Konjugat: Unconjugated