Insulin efsitora alfa, CAS 2131038-11-2

Product Description: Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: N/A

References: [1]Heise T, et al. Pharmacokinetic and pharmacodynamic properties of the novel basal insulin Fc (insulin efsitora alfa), an insulin fusion protein in development for once-weekly dosing for the treatment of patients with diabetes. Diabetes Obes Metab. 2023 Apr;25(4):1080-1090. /[2]Moyers JS, et al. Preclinical Characterization of LY3209590, a Novel Weekly Basal Insulin Fc-Fusion Protein. J Pharmacol Exp Ther. 2022 Sep;382(3):346-355.

CAS Number: 2131038-11-2

Molecular Weight: N/A

Compound Purity: 99.80

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Insulin Receptor

• Artikelnummer: MEXHY-P99665-500UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99665-500UG
• Green Labware: Nein
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK