Product Description: Albinterferon alfa-2b is a type I interferon that activates novel genes and exerts potent antiviral and antiproliferative activity on target cells. Signaling by Albinterferon alfa-2b requires receptor-dependent activation of Stat1 and Stat2 to form a heterodimeric STAT that binds to the DNA-binding protein IRF-9 (p48) and forms ISGF-3 (IFN-stimulated gene factor 3). The driver genes are then further activated by ISGF-3 to achieve antiviral function[1].
Applications: COVID-19-immunoregulation
Formula: N/A
References: [1]Park C, et al. Immune response in Stat2 knockout mice. Immunity. 2000 Dec;13(6):795-804.