Lampalizumab, CAS 1278466-20-8

Product Description: Lampalizumab (RG 7417) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab can be used for age-related macular degeneration (AMD) research[1][2].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Yuan X, et al. Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. Haematologica. 2017 Mar;102(3):466-475./[2]Hanus J, et al. Current therapeutic developments in atrophic age-related macular degeneration. Br J Ophthalmol. 2016 Jan;100(1):122-7.

CAS Number: 1278466-20-8

Molecular Weight: 143.8 (kDa)

Compound Purity: 99.46

Research Area: Inflammation/Immunology

Solubility: H2O

Target: Complement System

• Artikelnummer: MEXHY-P99298-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99298-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK