Lanadelumab, CAS 1426055-14-2

Product Description: Lanadelumab (SHP643) is a human IgG1 monoclonal antibody against plasma kallikrein (pKal) with an Ki value of 0.12 nM. Lanadelumab inhibits both free and HMWK (high molecular weight kininogen)-bound pKal. Lanadelumab has the potential for the research of hereditary angioedema[1][2].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Riedl MA, et al. Lanadelumab demonstrates rapid and sustained prevention of hereditary angioedema attacks. Allergy. 2020 Nov;75(11):2879-2887./[2]Kenniston JA, et al. Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J Biol Chem. 2014 Aug 22;289(34):23596-608.

CAS Number: 1426055-14-2

Molecular Weight: N/A

Compound Purity: 99.57

Research Area: Inflammation/Immunology

Solubility: H2O

Target: Kallikrein

• Artikelnummer: MEXHY-P99110-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99110-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK