Lexatumumab, CAS 845816-02-6

Product Description: Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Belyanskaya LL, et al. Human agonistic TRAIL receptor antibodies Mapatumumab and Lexatumumab induce apoptosis in malignant mesothelioma and act synergistically with cisplatin. Mol Cancer. 2007 Oct 22;6:66./[2]Engesæter B, et al. Dacarbazine and the agonistic TRAIL receptor-2 antibody lexatumumab induce synergistic anticancer effects in melanoma. PLoS One. 2012;7(9):e45492.

CAS Number: 845816-02-6

Molecular Weight: 143.6 (kDa)

Compound Purity: 96.95

Research Area: Cancer

Solubility: H2O

Target: Apoptosis

• Artikelnummer: MEXHY-P99299-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99299-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK