Product Description: Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1[1].
Applications: COVID-19-immunoregulation
Formula: N/A
References: [1]Kyriakos P Papadopoulos, et al. A Phase I First-in-Human Study of Nesvacumab (REGN910), a Fully Human Anti-Angiopoietin-2 (Ang2) Monoclonal Antibody, in Patients with Advanced Solid Tumors. Clin Cancer Res. 2016 Mar 15;22(6):1348-55.
CAS Number: 1296818-77-3
Molecular Weight: N/A
Compound Purity: 99.11
Research Area: Inflammation/Immunology; Cardiovascular Disease
Solubility: H2O
Target: Others