Product Description: Pertuzumab (PBS), a humanized monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer.
Applications: Cancer-Kinase/protease
Formula: N/A
References: [1]Nahta R, et al. The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survivalof breast cancer cells. Cancer Res. 2004 Apr 1;64(7):2343-6./[2]Scheuer W, et al. Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor models. Cancer Res. 2009 Dec 15;69(24):9330-6.
CAS Number: 380610-27-5
Molecular Weight: N/A
Compound Purity: 99.10
Research Area: Cancer
Solubility: H2O
Target: EGFR