Product Description: Ponezumab (PF-04360365) is a humanised anti-amyloid IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves performance in mice in various models of learning and memory. Ponezumab can be used in study of Alzheimer's disease[1].
Applications: Neuroscience-Neurodegeneration
Formula: N/A
References: [1]Nicholas T, et al. Preliminary population pharmacokinetic modeling of PF-04360365, a humanized anti-amyloid monoclonal antibody, in patients with mild-to-moderate Alzheimer's disease[J]. Alzheimer's and Dementia, 2009, 5(4): P253.
CAS Number: 1178862-65-1
Molecular Weight: N/A
Compound Purity: 95.00
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: EGFR