Rademikibart, CAS 2648260-80-2

Product Description: Rademikibart (CBP-201) is a human monoclonal antibody targeting IL-4Rα with a KD of 20.7 pM when binding to human IL-4Rα epitopes. Rademikibart does not bind to IL-4Rα from other species. Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation and TARC production in PBMCs. Rademikibart has the potential for moderate-to-severe Th2 inflammatory diseases research[1].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Limin Zhang, et al. Preclinical immunological characterization of rademikibart (CBP-201), a next-generation human monoclonal antibody targeting IL-4Rα, for the treatment of Th2 inflammatory diseases. Sci Rep. 2023 Jul 31;13(1):12411.

CAS Number: 2648260-80-2

Molecular Weight: N/A

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Interleukin Related

• Artikelnummer: MEXHY-P990090-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P990090-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK